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王星宇，博士，副教授，硕士生导师。2008毕业于中国计量大学，获得生物技术工学学士学位。2014年毕业于中国海洋大学，师从梁兴国教授，获食品科学工学博士学位。2015年11月入职bat365在线平台官网。以第一和通讯作者身份发表研究论文16篇，其中SCI收录14篇。参与译著《食品分析实验指导》，副主编《食品安全检测技术》两本食品专业教材。主持国家自然科学基金青年项目1项，陕西省重点研发项目2项、中央高校基本科研业务基金2项、陕西阔成检测公司横向课题1项；参与国家自然科学基金面上项目，陕西省重点研发计划和陕西省林业厅项目等共7项；授权国家发明专利3项。（以上信息截止于2022年7月）

邮箱：wangxingyu@snnu.edu.cn 

研究方向：

1. 植物源miRNA的消化吸收机制及其跨界调控作用。Stability and absorption mechanism of plant-derived miRNAs in mammalian gastrointestinal environment and their potential regulatory effects in cross-kingdom fashion.

2. 高灵敏度和特异性的核酸快速检测定量分析方法及其在食品领域的应用。Qualitative and quantitative analysis methods for nucleic acids (e.g. DNA, RNA) with ultrahigh sensitivity and specificity, and their applications in food science and engineering.

3. 食品功能因子的作用机理和高稳定性高吸收率纳米载体的构建。Molecular mechanisms behind phenotypes of food bioactive compounds and the construction of nano-scale vectors for specific delivery with high stability and bioavailability.

主持项目：

1. 国家自然科学基金青年项目，31901653，植物食品miRNA在胃肠环境中的稳定性和吸收机理的研究，2020.1-2022.12，24.00万。

2. 陕西省农业领域重点研发项目，2022NY-091，基于包涵体内特异性DNA的羊乳掺假检测技术的研发与示范，2022.1-2023.12，8.00万。

3. 陕西省农业领域重点研发项目，2018NY-095，肉制品中食源性致病菌快速检测技术的研发与示范，2018.1-2020.12，15.00万。

4. 中央高校项教师自由探索项目，GK202003087，荧光量子点纳米材料辅助适配体扩增检测食源性致病菌的研究，2020.01-2021.12，6.00万。

5. 中央高校项教师自由探索项目，GK201603101，基于等温扩增的快速、可视化检测食品中有害微生物方法的研究，2016.1.1-2017.12.31，6.00万。

研究论文（*表示通讯作者）

1. Qin Xinshu, Wang Xingyu^*, Xu Ke, et al. “Synergistic antitumor effects of polysaccharides and anthocyanins from Lycium ruthenicum Murr. on human colorectal carcinoma LoVo cells and the molecular mechanism [J]”. Food Science & Nutrition, 2022, 124:1-13. (IF: 3.553)

2. Qin Xinshu, Wang Xingyu^*, Xu Ke, et al. “Digestion of Plant Dietary miRNAs Starts in the Mouth under the Protection of Coingested Food Components and Plant-Derived Exosome-like Nanoparticles [J] ”. Journal of Agricultural and Food Chemistry, 2022, 70, 4316-4327. (IF: 5.895)

3. Wang Xingyu^*, Ren X, Ning L, et al. “Stability and absorption mechanism of typical plant miRNAs in an in vitro gastrointestinal environment: basis for their cross-kingdom nutritional effects [J]”. The Journal of Nutritional Biochemistry, 2020, 81: 108376. (IF: 6.117)

4. Liang Qian, Wang Xingyu^*, Yang Shuo, et al. “Characterization of the antioxidative polysaccharides from Ziziphus jujube cv. Goutouzao and its tumor-inhibitory effects on human colorectal carcinoma LoVo cells via immunocyte activation [J]”. Journal of Food Biochemistry, 2020, 44(11): e13462. (IF: 3.654)

5. Ning Lufang, Wang Xingyu^*, Xu Ke, et al. “A Novel Isothermal Method using Rolling Circle Reverse Transcription for Accurate Amplification of Small RNA sequences [J]”. Biochimie, 2019, 163:137-141. (IF: 4.372)

6. Song Shixi, Wang Xingyu^*, Xu Ke, et al. “Rapid identification and quantitation of the viable cells of Lactobacillus casei in fermented dairy products using an aptamer-based strategy powered by a novel cell-SELEX protocol [J]”. Journal of Dairy Science, 2019, 102(12): 10814-10824. (IF:  4.225)

7. Song Shixi, Wang Xingyu^*, Xu Ke, et al. “Visualized detection of vibrio parahaemolyticus in food samples using dual-functional aptamers and cut-assisted rolling circle amplification [J]”. Journal of Agricultural and Food Chemistry, 2019, 67(4): 1244-1253. (IF: 5.895)

8. Song Shixi, Wang Xingyu^*, Xu Ke, et al. “Selection of highly specific aptamers to Vibrio parahaemolyticus using cell-SELEX powered by functionalized graphene oxide and rolling circle amplification [J]”. Analytica Chimica Acta, 2019, 1052: 153-162. (IF: 6.911)

9. Wang Xingyu, Gao Aning, Jiao Yadong, et al. “Antitumor effect and molecular mechanism of antioxidant polysaccharides from Salvia miltiorrhiza Bunge in human colorectal carcinoma LoVo cells [J]”. International Journal of Biological Macromolecules, 2018, 108: 625-634. (IF: 8.025)

10. Wang Xingyu, Liang Xingguo^*, “Azobenzene-modified antisense oligonucleotides for site-specific cleavage of RNA with photocontrollable property”, RSC Advances, 2016, 6(96): 93398-93402. (IF: 4.036)

11. Wang Xingyu, Li Can, Gao Xiaomeng, et al. “Preparation of small RNAs using rolling circle transcription and site-specific RNA disconnection [J]”. Molecular Therapy-Nucleic Acids, 2015, 4(1): e215. (IF: 10.183)

12. Wang Xingyu, Ding Mei, Liu Zihui, et al. “Synthesis of a chitosan-based functional biopolymer with both catalytic and binding groups for protein and DNA hydrolysis [J]”. RSC Advances, 2015, 5(25): 19541-19551. (IF: 4.036)

13. Wang Xingyu, Yu Xin, Wang Xiaoliang, et al. “Highly specific DNA detection from massive background nucleic acids based on rolling circle amplification of target dsDNA [J]”. RSC Advances, 2014, 4(72): 38293-38299. (IF: 4.036)

14. Wang Xingyu, Wang Dongfeng, Liang Peng, et al. “Synthesis and properties of an insoluble chitosan resin modified by azamacrocycle copper (II) complex for protein hydrolysis [J]”. Journal of Applied Polymer Science, 2013, 128(5): 3280-3288. (IF: 3.057)