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袁莉，女，中共党员，博士，教授，硕士生导师。荣获西安市科协青年托举人才。主要从事食品分子营养学和毒理学领域的相关教学与科研工作。主讲《食品分子生物学》和《食品毒理学》课程。近年来，主持研究国家自然科学基金项目2项、陕西省技术创新引导计划项目1项及厅局级项目2项等。以第一作者或通讯作者发表学术论文50余篇，其中SCI收录30余篇，授权发明专利5件，参编教材2部，参与获得陕西省高等学校科学技术一等奖和二等奖各1项。

主要研究方向：

1）食品功能因子营养机制研究

2）食品活性成分功能稳态化及增效体系研究

3）食品加工有害产物毒性及控制研究

代表性成果：

1) ZhuLin Wang, Lin Shi, Hao Li, Wei Song, JianKe Li, Li Yuan*, Selenium-enriched black soybean protein prevents benzo(a)pyrene-induced pyroptotic colon damage and gut dysbacteriosis, Journal of Agricultural and Food Chemistry, 2022, 70, 12629-12640.

2) Xiao Wang, Li Yuan*, Hong Deng, Zhong Zhang, Structural characterization and stability study of green synthesized starch stabilized silver nanoparticles loaded with isoorientin, Food Chemistry, 2021, 338: 127807.

3) Shenyuan He, Xueyi Li, Cuiqin Li, Hong Deng, Yuyu Shao, Li Yuan*, Isoorientin attenuates benzo[a]pyrene-induced colonic injury and gut microbiota disorders in mice, Food Research International, 2019, 126:108599.

4) Wang Xiao, Yuan Li*, Deng Hong, Zhang Zhong. Structural characterization and stability study of green synthesized starch stabilized silver nanoparticles loaded with isoorientin, Food Chemistry, 2021,338:127807.

5) Li Yuan*, Xueyi Li, Shenyuan He, Chunxia Gao, Chengtao Wang, Yuyu Shao, Effects of natural flavonoid isoorientin on growth performance and gut microbiota of mice, Journal of Agricultural and Food Chemistry, 2018, 66:9777-9784.

6) Li Yuan*, Junyi Liu, Hong Deng, Chunxia Gao, Benzo[a]pyrene induces autophagicand pyroptotic death simultaneously in HL-7702 human normal liver cells, Journal of Agricultural and Food Chemistry, 2017, 65: 9763-9773.

7) Li Yuan*, Xiao Han, Wenfeng Li, Daoyuan Ren, Xingbin Yang, Isoorientin prevents hyperlipidemia and liver injury by regulating lipid metabolism, antioxidant capability, and inflammatory cytokine release in high-fructose-fed mice, Journal of Agricultural and Food Chemistry, 2016, 64, 2682-2689

8) Li Yuan, Shuping Wei, Jing Wang, Xuebo Liu*, Isoorientin induces apoptosis and autophagy simultaneously by ROS-related P53, PI3K/Akt, JNK and P38 signaling pathways in HepG2 cancer cells, Journal of Agricultural and Food Chemistry,2014, 62 (23): 5390-400.

9) Li Yuan, Jing Wang, Haifang Xiao, Chunxia Xiao, Wanqiang Wu, Xuebo Liu*, MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells, Food and Chemical Toxicology, 2013, 53: 62-68.

10) Li Yuan, Jing Wang, Haifang Xiao, Chunxia Xiao, Yutang Wang, Xuebo Liu*, Isoorientin induces apoptosis through mitochondrial dysfunction and inhibition of PI3K/Akt signaling pathway in HepG2 cancer cells, Toxicology and Applied Pharmacology, 2012, 265: 83-92.

11) 李浩,袁莉*,骆莹. 食品有害物诱发细胞焦亡的研究进展. 食品与发酵工业, 2022,48(13)321-327.

12) 李庆舒, 程琳, 邓红, 张忠, 袁莉*. 三种多酚与牛血清蛋白相互作用的初步研究. 食品与发酵工业, 2020, 46(3):180-187.

13) 袁莉*, 高春霞, 邓红, 刘俊义.食品有害物苯并(α)芘及其诱导细胞死亡的研究进展.食品与生物技术学报. 2017, 36(6): 561-568.

14) 袁莉, 吴雨晨, 任骁萌，刘学波*. 荭草素和异荭草素抗氧化活性及对肝癌细胞增殖的影响.食品科学技术学报, 2013, 31(6):21-27.

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